{
  "data": {
    "id": "stat_W560S45SS5JAN21YBEKN25HTMW",
    "url": "https://statorigin.org/stat/stat_W560S45SS5JAN21YBEKN25HTMW",
    "indicator": {
      "slug": "large-company-small-molecule-share-of-phase-i-clinical-trial-starts",
      "name": "Large company small molecule share of Phase I clinical trial starts",
      "definition": "Percentage of Phase I clinical trial starts sponsored by large pharmaceutical companies that investigate small molecule drugs."
    },
    "industry": [
      {
        "slug": "pharmaceuticals",
        "name": "Manufacture of basic pharmaceutical products and pharmaceutical preparations",
        "isic": "C21",
        "is_primary": true
      }
    ],
    "region": {
      "code": "GLOBAL",
      "name": "Global",
      "type": "world"
    },
    "period": {
      "start": "2022-01-01",
      "end": "2022-12-31",
      "type": "year"
    },
    "value": 61,
    "value_text": "61%",
    "unit": "percent",
    "currency": null,
    "scale": "1",
    "value_type": "actual",
    "source": {
      "org": "IQVIA Institute",
      "org_short_name": "IQVIA",
      "org_url": "https://www.iqvia.com",
      "org_tier": 3,
      "document_title": "Global R&D Trends 2026",
      "document_url": "https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2025",
      "document_type": "press_release",
      "locator": "Exhibit 21: Small molecule share of trial starts by phase and company segment, 2016–2025",
      "quote": "The recent increase in the proportion of small molecule trials in Phase I has been driven by a combination of stabilization of small molecule share among EBPs and an increasing share of small molecule trials among larger companies, where the small molecule share increased from 61% in 2022 to 66% in 2025.",
      "published_date": null,
      "accessed_at": "2026-09-15",
      "license": "see-source",
      "url_status": "ok"
    },
    "verification": "verified",
    "verified_by": "seed:auto-extract-v1",
    "verified_at": "2026-09-17T07:16:01.811Z",
    "confidence": 0.9,
    "is_secondhand": false,
    "supersedes": null,
    "superseded_by": null,
    "is_current": true,
    "citation": {
      "apa": "IQVIA Institute. (2022). Global R&D Trends 2026. Retrieved September 15, 2026, from https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2025. Via StatOrigin, https://statorigin.org/stat/stat_W560S45SS5JAN21YBEKN25HTMW",
      "bibtex": "@misc{iqvia2022large25htmw,\n  author       = {{IQVIA Institute}},\n  title        = {Global R\\&D Trends 2026},\n  year         = {2022},\n  howpublished = {StatOrigin, https://statorigin.org},\n  url          = {https://statorigin.org/stat/stat_W560S45SS5JAN21YBEKN25HTMW},\n  note         = {Original source: https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2025. Accessed September 15, 2026.}\n}"
    },
    "updated_at": "2026-09-17T07:16:01.811Z",
    "contested_by": [],
    "related": []
  },
  "meta": {
    "attribution": "Data from StatOrigin (https://statorigin.org), CC BY 4.0. Attribution required.",
    "license": "https://creativecommons.org/licenses/by/4.0/",
    "docs": "https://statorigin.org/docs/api",
    "total": 1
  }
}