Small molecule share of Phase I trial starts

Share of Phase I clinical trial starts that examine small molecule drugs.

Unit Percent Industry Healthcare

Records
6
Regions
1
Period
2016–2025
Sources
1
Verification 6 verified data points Updated 17 Sep 2026 Last verified 17 Sep 2026 Next update Sources typically refresh annually

The chart

Over time

Global over time. Forecasts are dashed with hollow markers; the underlying values are one click away under the chart.

Small molecule share of Phase I trial starts

Global, 2016 to 2025

3 observations · 2016 to 2025

No figure published for these periods

Small molecule share of Phase I trial startsSmall molecule share of Phase I trial starts. 3 observations from 2016 to 2025, ranging from 60% to 72%. Latest value 62% (2025). % 0 20 40 60 80 2016 2018 2020 2022 2024 72% 62%
Small molecule share of Phase I trial startsSmall molecule share of Phase I trial starts. 3 observations from 2016 to 2025, ranging from 60% to 72%. Latest value 62% (2025). % 0 20 40 60 80 2016 2018 2020 2022 2024 72% 62%
Small molecule share of Phase I trial startsSmall molecule share of Phase I trial starts. 3 observations from 2016 to 2025, ranging from 60% to 72%. Latest value 62% (2025). % 0 20 40 60 80 2016 2018 2020 2022 2024 72% 62%
View the underlying data
Small molecule share of Phase I trial starts
Period Type Value
2016 Actual 72%
2023 Actual 60%
2025 Actual 62%
Source: IQVIA · CC BY 4.0 · statorigin.org
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Every record

All records

6 records · 1 region · 2016–2025

Small molecule share of Phase I trial starts: every record, grouped by region, newest first.
Period Value Source Type
Global 6 records
2025 62% IQVIA · 31 Dec 2025 actual
2025 62% IQVIA · 31 Dec 2025 actual
2023 60% IQVIA · 31 Dec 2023 actual
2023 60% IQVIA · 31 Dec 2023 actual
2016 72% IQVIA · 31 Dec 2016 actual
2016 72% IQVIA · 31 Dec 2016 actual

Primary documents

Sources

2 documents. Each links to the publisher's own copy.

Document Publisher Published Data points
Global R&D Trends 2026 IQVIA 3
Global R&D Trends 2026 IQVIA 3

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StatOrigin. (2026). Small molecule share of Phase I trial starts. Retrieved from https://statorigin.org/indicators/small-molecule-share-of-phase-i-trial-starts