Phase I small molecule clinical trial share vs Antibody-drug conjugate trial starts

In 2025, phase I small molecule clinical trial share worldwide was 62%; antibody-drug conjugate trial starts was 349.

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The series

Over time

Global, annual figures, spaced by time from 2023 to 2025 . Different units, drawn on separate scales and clipped to the years both series publish; earlier history stays on each indicator’s own page. Read the values, not the heights.

Phase I small molecule clinical trial share

Unit: % · 2 observations

Line chart
Phase I small molecule clinical trial sharePhase I small molecule clinical trial share. 2 observations from 2023 to 2025, ranging from 60% to 62%. Latest value 62% (2025). % 0 20 40 60 80 2023 2024 2025 60% 62%
Phase I small molecule clinical trial sharePhase I small molecule clinical trial share. 2 observations from 2023 to 2025, ranging from 60% to 62%. Latest value 62% (2025). % 0 20 40 60 80 2023 2024 2025 60% 62%
Phase I small molecule clinical trial sharePhase I small molecule clinical trial share. 2 observations from 2023 to 2025, ranging from 60% to 62%. Latest value 62% (2025). % 0 20 40 60 80 2023 2024 2025 60% 62%
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Phase I small molecule clinical trial share
Period Type Value
2023 Actual 60%
2025 Actual 62%
Source: IQVIA · CC BY 4.0 · Full series

Antibody-drug conjugate trial starts

Unit: count · 3 observations

Line chart
Antibody-drug conjugate trial startsAntibody-drug conjugate trial starts. 3 observations from 2023 to 2025, ranging from 233 to 349. Latest value 349 (2025). 0 100 200 300 400 2023 2024 2025 233 349
Antibody-drug conjugate trial startsAntibody-drug conjugate trial starts. 3 observations from 2023 to 2025, ranging from 233 to 349. Latest value 349 (2025). 0 100 200 300 400 2023 2024 2025 233 349
Antibody-drug conjugate trial startsAntibody-drug conjugate trial starts. 3 observations from 2023 to 2025, ranging from 233 to 349. Latest value 349 (2025). 0 100 200 300 400 2023 2024 2025 233 349
View the underlying data
Antibody-drug conjugate trial starts
Period Type Value
2023 Actual 233
2024 Actual 282
2025 Actual 349
Source: ClinicalTrials.gov · CC BY 4.0 · Full series

Shared periods

Side by side

2 periods are published for both series as annual figures on the same basis. Comparing anything else would mean comparing different periods.

Period Phase I small molecule clinical trial share Antibody-drug conjugate trial starts
2023 60% IQVIA 233 ClinicalTrials.gov
2025 62% IQVIA 349 ClinicalTrials.gov

Provenance

Where these numbers come from

Phase I small molecule clinical trial share

Percentage of Phase I clinical trial starts that evaluate small molecule drugs.

2 observations charted in Global (of 3 annual records) · source organisations: IQVIA

Antibody-drug conjugate trial starts

Count of interventional studies whose record mentions an antibody-drug conjugate by class or by payload/brand stem (deruxtecan, vedotin, govitecan, emtansine, tirumotecan, rezetecan and others) whose start date falls in the period. The region is a site country: a study counts for every country where it lists a site, so regional counts overlap and do not sum to the global count.

3 observations charted in Global (of 6 annual records) · source organisations: ClinicalTrials.gov

Data published under CC BY 4.0. Series A as JSON · Series B as JSON

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