Large company small molecule share of Phase I clinical trial starts

The recent increase in the proportion of small molecule trials in Phase I has been driven by a combination of stabilization of small molecule share among EBPs and an increasing share of small molecule trials among larger companies, where the small molecule share increased from 61% in 2022 to 66% in 2025.

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APA

IQVIA Institute. (2022). Global R&D Trends 2026. Retrieved September 15, 2026, from https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2025. Via StatOrigin, https://statorigin.org/stat/stat_W560S45SS5JAN21YBEKN25HTMW

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MLA

IQVIA Institute. "Global R&D Trends 2026." 2022, https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2025. Accessed 15 Sept. 2026 via StatOrigin, https://statorigin.org/stat/stat_W560S45SS5JAN21YBEKN25HTMW.

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Chicago

IQVIA Institute. "Global R&D Trends 2026." 2022. https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2025. Accessed September 15, 2026. Cited from StatOrigin, https://statorigin.org/stat/stat_W560S45SS5JAN21YBEKN25HTMW.

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BibTeX

@misc{iqvia2022large25htmw, author = {{IQVIA Institute}}, title = {Global R\&D Trends 2026}, year = {2022}, howpublished = {StatOrigin, https://statorigin.org}, url = {https://statorigin.org/stat/stat_W560S45SS5JAN21YBEKN25HTMW}, note = {Original source: https://www.iqvia.com/insights/the-iqvia-institute/reports-and-publications/reports/global-trends-in-r-and-d-2025. Accessed September 15, 2026.} }

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Record last modified 17 September 2026. Value type: actual. Update cadence: annual. This page is permanently addressable at statorigin.org/stat/stat_W560S45SS5JAN21YBEKN25HTMW.